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Table 3 Regional disparities in pharmaceutical access and expenditure: key drivers

From: Out-of-pocket pharmaceutical expenditure and potential misuse of public resources - analysis in the Italian context

Macro Area

Average Income (€)

OOP Pharmaceutical procapita Spending (€)

AIFA Notes Exceeding National Average (Coverage Data)

Key Observations

Northern Regions

30,000

13,7

1, 1/48, 28, 36, 48, 51, 74, 75, 82, 85, 90, 92, 93, 97,99, 100

Higher income, lower OOP spending. Presumed greater general AIFA Note utilization contributes to lower OOP costs, but cultural differences play a role in brand-name preferences.

Central Regions

25,000

20,3

39, 42, 65

Moderate income, moderate OOP spending. Mixed adherence to AIFA Notes contributes to intermediate OOP costs. Reimbursement criteria have an impact, cultural differencs may play a small role

Southern Regions

18,000

23,9

2, 8, 13, 15, 31, 55, 56, 66, 79, 83, 84, 87, 88, 89, 91, 95, 96

Lower income, higher OOP spending. Inappropriate or less restrictive use of certain AIFA Notes, contributes to high OOP costs, coupled with cultural preferences for brand-name drugs and potential information gaps.