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Table 3 Costs in the United States

From: Cost-utility analysis of olaparib assisted targeted therapy for BRCA mutation HER2-negative early breast cancer in China and in the United States

Parameters name

Base($)

Range ($)

Distribution

Source

Olaparib(150 mg)

115.72

61.13 ~ 125.78

–

Redbook,drug.com

Olaparib(per cycle)

13,886.4

7335.6 ~ 15,093.6

Triangle

–

Placebo (per cycle)

–

–

–

–

Paclitaxel(per cycle)

5328.14

4844.58 ~ 5860.43

Triangle

[9]

BRCA1/2 test

2759.03

1468.53 ~ 4405.6

Triangle

[7, 8]

Lab test(per cycle)

350.62

262.96 ~ 438.26

Triangle

[9]

Nursing(per cycle)

3458.74

2766.58 ~ 4149.87

Triangle

[13]

Routine follow-up(per cycle)

1252.27

920.08 ~ 1584.45

Triangle

[8]

CT(per cycle)

878.43

702.42 ~ 1054.11

Triangle

[10]

Mammography(per cycle)

171.01

85.51 ~ 256.52

Triangle

[7]

MRI(per cycle)

677.72

338.86 ~ 1016.58

Triangle

[7]

Adverse reaction

    

Anemia

801.96

641.56 ~ 962.35

Triangle

[11]

Fatigue

147.47

117.97 ~ 176.96

Triangle

[10]

Neutropenia

920.84

736.67 ~ 1105.01

Triangle

[11]

  1. CT Computed Tomography; MRI Magnetic Resonance Imaging