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Table 5 Results of the sensitivity analyses

From: Cost-effectiveness of proton beam therapy vs. conventional radiotherapy for patients with brain tumors in Sweden: results from a non-randomized prospective multicenter study

Scenario

Incremental cost

mean (95% CI)

Incremental QALY

mean (95% CI)

ICER

mean (95% CI)

Base case

1,372 (-4,914–7,659)

-0.049 (-0.195–0.097)

Dominated

1. Versteegh et al. mapping algorithm (50)

1,372 (-4,914–7,659)

-0.023 (-0.186–0.140)

Dominated

2. McKenzie and van der Pol mapping algorithm (51)

1,372 (-4,914–7,659)

-0.034 (-0.18–0.113)

Dominated

3. Dutch tariffs to estimate QLU-C10D utility scores

1,372 (-4,914–7,659)

-0.045 (-0.176–0.865)

Dominated

4. German tariffs to estimate the QLU-C10D utility scores

1,372 (-4,914–7,659)

-0.046 (-0.180–0.089)

Dominated

5. Complete case analysis

1,372 (-4,914–7,659)

-0.003 (-0.116–0.109)

Dominated

  1. Abbreviations PBT – Proton beam therapy, CI – Confidence interval, CRT– Conventional radiotherapy, ICER – Incremental cost effectiveness ratio, QALY – Quality adjusted life year. Costs in 2023 US$