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Table 1 Input parameters

From: Modelled cost-effectiveness analysis of the Support and Treatment After Replacement (STAR) care pathway for chronic pain after total knee replacement compared with usual care

 

Y1

Y2

Y3

Y4

Y5

Source

Base case

Transition probabilities

Usual care CP to CP

0.494

0.368

0.388

0.400

0.406

STAR trial (Y1),

COASt (Y2-Y5)

Usual care CP to NCP

0.506

0.632

0.612

0.600

0.594

Usual care NCP to CP

0.000

0.050

0.042

0.031

0.037

Usual care NCP to NCP

0.000

0.950

0.958

0.969

0.963

STAR care pathway CP to CP

0.355

0.368

0.388

0.400

0.406

STAR care pathway CP to NCP

0.645

0.632

0.612

0.600

0.594

STAR care pathway NCP to CP

0.000

0.050

0.042

0.031

0.037

STAR care pathway NCP to NCP

0.000

0.950

0.958

0.969

0.963

Quality Adjusted Life Years

Usual care CP

0.465

0.556

0.607

0.642

0.698

STAR trial (level),

COASt (progression)

Usual care NCP

0.539

0.730

0.727

0.716

0.702

STAR care pathway CP

0.484

0.572

0.621

0.654

0.708

STAR care pathway NCP

0.560

0.742

0.739

0.728

0.714

Cost (£)

STAR care pathway

191

0

0

0

0

STAR trial

Prescriptions CP

100

88

91

91

91

STAR trial (level),

CPRD (progression)

Prescriptions NCP

22

18

17

17

18

Medical consultations CP

166

143

137

137

125

STAR trial (level),

CPRD (progression)

Medical consultations NCP

62

51

48

46

48

Usual care hospital admissions CP

2,972

898

464

65

24

STAR trial (level),

COASt (progression)

Usual care hospital admissions NCP

1,057

386

331

82

249

STAR care pathway hospital admissions CP

1,265

898

464

65

24

STAR trial (level),

COASt (progression)

STAR care pathway hospital admissions NCP

1,302

386

331

82

249

Sensitivity analysis - scenario analysis

Quality Adjusted Life Years– Scenario 1

CP

0.477

0.566

0.616

0.650

0.704

STAR trial (level),

COASt (progression)

NCP

0.555

0.739

0.736

0.725

0.711

Transition probabilities– Scenario 2

Usual care CP to CP

0.500

0.368

0.388

0.400

0.406

STAR trial (Y1),

COASt (Y2-Y5)

Usual care CP to NCP

0.500

0.632

0.612

0.600

0.594

Usual care NCP to CP

0.000

0.050

0.042

0.031

0.037

Usual care NCP to NCP

1.000

0.950

0.958

0.969

0.963

STAR care pathway CP to CP

0.357

0.368

0.388

0.400

0.406

STAR care pathway CP to NCP

0.643

0.632

0.612

0.600

0.594

STAR care pathway NCP to CP

0.222

0.050

0.042

0.031

0.037

STAR care pathway NCP to NCP

0.778

0.950

0.958

0.969

0.963

Cost (£)– Scenario 3

Hospital admissions CP

1,935

898

464

65

24

STAR trial (level),

COASt (progression)

Hospital admissions NCP

1,237

386

331

82

249

 
  1. Level - refers to the data used to estimate the initial year one input parameters
  2. Progression - refers to the data used to estimate the change over time which was then applied to the initial year one input parameters to estimate subsequent years
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Cost Effectiveness and Resource Allocation

ISSN: 1478-7547

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