Fig. 1

Decision strategies: intervention regimen provides pemigatinib 13.5Â mg per day, comparator 1 provides mFOLFOX a, comparator 2 provides 5-FU b, and the cost-effectiveness analysis framework c. ICC intrahepatic cholangiocarcinoma, FGFR2 fibroblast growth factor receptor 2, mFOLFOX a combination of oxaliplatin, folinic acid, and fluorouracil, 5-FU fluorouracil, ICER incremental cost-effectiveness ratio, INMB incremental net monetary benefit, EVPI expected value of perfect information