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Table 1 Primary Characteristics of the Studies

From: Cost-effectiveness analysis of dapagliflozin in the management of heart failure with reduced ejection fraction (HFrEF): a systematic review

Study (year)

Country

Perspective

Currency/year

Economic study type

Time horizon

Discount rate

Paritzo et ,al. 2021

UK

Healthcare Payer

US Dollars/2020

Markov model

Life time

3%

Krittayaphong et al., 2020

Thailand

Healthcare System

Thai Baht/2020

Markov model

Life time

3%

Mendoza et al., 2021

Philippines

Public Healthcare provider

Philippine Peso/2021

Markov model

Life time

3%

Savira et al., 2020

Australia

Australian Healthcare

Australian Dollars /2019

Markov model

Life time

5%

Isaza et al., 2021

US

US Healthcare Sector

US Dollars/2020

Markov model

Life time

3%

McEwan et al., 2020

UK, Germany, and Spain

Euro Multi-national Healthcare System

British Pound/2019

Markov model

Life time

Spain and Germany: 3%

Euro/2019

UK: 3.5%

Yao et al., 2020

China

Chinese Healthcare Payers

Chinese Renminbi/2020

Markov model

15 years

4.2%

Liao et al., 2021

South Korea, Australia, Taiwan, Japan, and Singapore

Asia–Pacific Region Healthcare Systems

US Dollars/2020

Markov model

  18 months

3%

  30 years

Gil-Rojas, 2021

Colombia

Colombian Health System

US Dollars/2020

Markov model

  5 years in the base case

5%

  10 years in sensitivity analyses

  16 years for the life expectancy analysis

Jiang et al., 2021

China

Chinese Medical and Health System

US Dollars/2021

Markov model

  5 years

5%

  10 years

  15 years

  20 years