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Table 4 Estimated QALYs for different patient subgroups

From: Cost-utility analysis of total knee arthroplasty alone and in comparison with post-surgical rehabilitation and conservative treatment in the Republic of Kazakhstan

Variable

Type of intervention

Test of difference for QALY gained: MANOVA

Test of difference for Cost per QALY: MANOVA

Conservative treatment

TKA

TKA with rehabilitation

n = 122

n = 62

n = 60

QALY gained

Cost per QALY

QALY gained

Cost per QALY

QALY gained

Cost per QALY

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

F

p-value

F

p-value

Age, years

  ≥ 65

0.28

0.36

26561.49

13661.86

1.75

0.77

5756.39

15493.72

2.43

0.34

1469.48

240.33

99.888

 < 0.001

55.017

 < 0.001

  < 65

0.19

0.14

36127.79

22512.10

0.81

0.53

7710.43

5122.23

1.28

0.49

3270.74

1848.88

Gender

 Male

0.27

0.32

30369.68

20907.10

1.51

0.84

6668.43

15421.07

1.57

0.68

2832.22

1782.86

58.329

 < 0.001

37.233

 < 0.001

 Female

0.15

0.06

31994.08

10088.39

1.40

0.81

5481.00

5807.60

2.39

0.41

1444.48

282.74

Stage of osteoarthritis

 Stage 3

0.25

0.35

31731.98

17469.50

1.47

0.78

4294.71

4041.79

1.64

0.80

2879.81

2007.67

0.018

0.893

0.632

0.428

 Stage 4

0.22

0.17

29535.44

20252.43

1.51

1.04

14,777.76

28529.46

1.74

0.39

2140.42

328.10

BMI

  < 25.0

0.26

0.34

30901.42

18140.63

1.34

0.91

5615.30

4981.50

1.95

0.58

1918.60

518.39

3.007

0.053

1.949

0.146

 25.0–29.9

    

1.35

0.45

3114.80

959.90

1.85

0.00

1775.40

0.00

  ≥ 30.0

0.22

0.18

30632.85

19621.27

1.72

0.85

8975.59

21651.69

1.08

0.62

4315.06

2266.39

Place of treatment

 Metropolis

    

1.42

0.79

7442.21

16567.13

1.62

0.91

4297.67

3083.06

0.937

0.336

0.015

0.901

 Regional

    

1.59

0.89

9922.52

20369.16

1.80

0.50

2646.72

625.88

Revision TKA

 Absent

    

1.47

0.78

4294.71

4041.79

1.36

0.85

3776.41

2375.60

n/a

n/a

n/a

n/a

 Present

        

1.77

0.59

2017.91

527.04

  1. BMI Body Mass Index, TKA Total Knee Arthroplasty, QALY Quality-adjusted Life Years, USD United States Dollars
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Cost Effectiveness and Resource Allocation

ISSN: 1478-7547

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