Figure 1

Effect of the difference in vaccine cost per dose on budget and effect. Reduction in diarrhoea events (left Y-axis) and relative change of vaccine budget constraint (=100%) (right Y-axis) as a function of the relative cost difference per vaccine dose. Assumptions: vaccine budget, $200,000; 2-dose vaccine efficacy (strategy A), 60%; 3- dose vaccine efficacy (strategy B), 65%; target vaccine coverage, 75%; 2-dose vaccine cost per dose (strategy A), $13.00; 3- dose vaccine cost per dose (strategy B), allowed to vary.